Synonymous Codon Pair Recoding of the HIV-1 env Gene Affects Virus Replication Capacity

Synonymous codon pair deoptimization is an efficient strategy for virus attenuation; however, the underlying mechanism remains controversial. Here, we optimized and deoptimized the codon pair bias (CPB) of the human immunodeficiency virus type 1 (HIV-1) envelope (env) gene to investigate the influen...

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Detalles Bibliográficos
Autores principales: Jordan-Paiz, Ana, Franco, Sandra, Martinez, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304268/
https://www.ncbi.nlm.nih.gov/pubmed/34209946
http://dx.doi.org/10.3390/cells10071636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304268/
https://www.ncbi.nlm.nih.gov/pubmed/34209946
http://dx.doi.org/10.3390/cells10071636

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