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Schizophrenia-Like Behavioral Impairments in Mice with Suppressed Expression of Piccolo in the Medial Prefrontal Cortex

Piccolo, a presynaptic cytomatrix protein, plays a role in synaptic vesicle trafficking in the presynaptic active zone. Certain single-nucleotide polymorphisms of the Piccolo-encoding gene PCLO are reported to be associated with mental disorders. However, a few studies have evaluated the relationshi...

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Detalles Bibliográficos
Autores principales: Nitta, Atsumi, Izuo, Naotaka, Hamatani, Kohei, Inagaki, Ryo, Kusui, Yuka, Fu, Kequan, Asano, Takashi, Torii, Youta, Habuchi, Chikako, Sekiguchi, Hirotaka, Iritani, Shuji, Muramatsu, Shin-ichi, Ozaki, Norio, Miyamoto, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304324/
https://www.ncbi.nlm.nih.gov/pubmed/34206873
http://dx.doi.org/10.3390/jpm11070607