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Direct Measurement of B Lymphocyte Gene Expression Biomarkers in Peripheral Blood Transcriptomics Enables Early Prediction of Vaccine Seroconversion

Peripheral blood transcriptome is a highly promising area for biomarker development. However, transcript abundances (TA) in these cell mixture samples are confounded by proportions of the component leukocyte subpopulations. This poses a challenge to clinical applications, as the cell of origin of an...

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Detalles Bibliográficos
Autores principales: Huang, Dan, Liu, Alex Y. N., Leung, Kwong-Sak, Tang, Nelson L. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304400/
https://www.ncbi.nlm.nih.gov/pubmed/34202032
http://dx.doi.org/10.3390/genes12070971