Engineering of Streptoalloteichus tenebrarius 2444 for Sustainable Production of Tobramycin

Tobramycin is a broad-spectrum aminoglycoside antibiotic agent. The compound is obtained from the base-catalyzed hydrolysis of carbamoyltobramycin (CTB), which is naturally produced by the actinomycete Streptoalloteichus tenebrarius. However, the strain uses the same precursors to synthesize several...

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Detalles Bibliográficos
Autores principales: Mitousis, Lena, Maier, Hannes, Martinovic, Luka, Kulik, Andreas, Stockert, Sigrid, Wohlleben, Wolfgang, Stiefel, Alfred, Musiol-Kroll, Ewa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304502/
https://www.ncbi.nlm.nih.gov/pubmed/34299618
http://dx.doi.org/10.3390/molecules26144343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304502/
https://www.ncbi.nlm.nih.gov/pubmed/34299618
http://dx.doi.org/10.3390/molecules26144343

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