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Cell Surface Binding and Lipid Interactions behind Chemotherapy-Drug-Induced Ion Pore Formation in Membranes

Chemotherapy drugs (CDs) disrupt the lipid membrane’s insulation properties by inducing stable ion pores across bilayer membranes. The underlying molecular mechanisms behind pore formation have been revealed in this study using several methods that confirm molecular interactions and detect associate...

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Detalles Bibliográficos
Autores principales: Ashrafuzzaman, Md., Khan, Zahid, Alqarni, Ashwaq, Alanazi, Mohammad, Alam, Mohammad Shahabul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304557/
https://www.ncbi.nlm.nih.gov/pubmed/34209282
http://dx.doi.org/10.3390/membranes11070501