Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease

SIMPLE SUMMARY: The Hedgehog/GLI (Hh/GLI) pathway plays a major role during development and it is commonly dysregulated in many diseases, including cancer. This highly concerted series of ligands, receptors, cytoplasmic signaling molecules, transcription factors, and co-regulators is involved in reg...

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Detalles Bibliográficos
Autores principales: Sigafoos, Ashley N., Paradise, Brooke D., Fernandez-Zapico, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304605/
https://www.ncbi.nlm.nih.gov/pubmed/34298625
http://dx.doi.org/10.3390/cancers13143410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304605/
https://www.ncbi.nlm.nih.gov/pubmed/34298625
http://dx.doi.org/10.3390/cancers13143410

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