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Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease

SIMPLE SUMMARY: The Hedgehog/GLI (Hh/GLI) pathway plays a major role during development and it is commonly dysregulated in many diseases, including cancer. This highly concerted series of ligands, receptors, cytoplasmic signaling molecules, transcription factors, and co-regulators is involved in reg...

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Detalles Bibliográficos
Autores principales:	Sigafoos, Ashley N., Paradise, Brooke D., Fernandez-Zapico, Martin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304605/ https://www.ncbi.nlm.nih.gov/pubmed/34298625 http://dx.doi.org/10.3390/cancers13143410

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