Discovery of Novel 2,4-Dianilinopyrimidine Derivatives Containing 4-(Morpholinomethyl)phenyl and N-Substituted Benzamides as Potential FAK Inhibitors and Anticancer Agents

Focal adhesion kinase (FAK) is responsible for the development and progression of various malignancies. With the aim to explore novel FAK inhibitors as anticancer agents, a series of 2,4-dianilinopyrimidine derivatives 8a–8i and 9a–9g containing 4-(morpholinomethyl)phenyl and N-substituted benzamide...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Chun, Shen, Kemin, Wang, Shijun, Wang, Zhijun, Su, Feng, Wu, Xi, Hu, Xiaoqin, Li, Mengyao, Han, Jing, Wu, Lintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304610/
https://www.ncbi.nlm.nih.gov/pubmed/34299462
http://dx.doi.org/10.3390/molecules26144187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304610/
https://www.ncbi.nlm.nih.gov/pubmed/34299462
http://dx.doi.org/10.3390/molecules26144187

Ejemplares similares