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17β-Estradiol-Induced Conformational Changes of Human Microsomal Triglyceride Transfer Protein: A Computational Molecular Modelling Study

Human microsomal triglyceride transfer protein (hMTP) plays an essential role in the assembly of apoB-containing lipoproteins, and has become an important drug target for the treatment of several disease states, such as abetalipoproteinemia, fat malabsorption and familial hypercholesterolemia. hMTP...

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Detalles Bibliográficos
Autores principales: Yang, Yong-Xiao, Li, Peng, Wang, Pan, Zhu, Bao-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304645/
https://www.ncbi.nlm.nih.gov/pubmed/34206252
http://dx.doi.org/10.3390/cells10071566