Ipragliflozin Ameliorates Diabetic Nephropathy Associated with Perirenal Adipose Expansion in Mice

Sodium glucose cotransporter-2 (SGLT2) inhibitors inhibit the development of diabetic nephropathy (DN). We determined whether changes in perirenal fat (PRAT) by a SGLT2 inhibitor ipragliflozin (Ipra) contribute to the suppression of DN development. High-fat diet (HFD)-fed mice were used as a DN mode...

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Detalles Bibliográficos
Autores principales: Okuma, Hideyuki, Mori, Kentaro, Nakamura, Suguru, Sekine, Tetsuo, Ogawa, Yoshihiro, Tsuchiya, Kyoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304702/
https://www.ncbi.nlm.nih.gov/pubmed/34298949
http://dx.doi.org/10.3390/ijms22147329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304702/
https://www.ncbi.nlm.nih.gov/pubmed/34298949
http://dx.doi.org/10.3390/ijms22147329

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