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Ipragliflozin Ameliorates Diabetic Nephropathy Associated with Perirenal Adipose Expansion in Mice

Sodium glucose cotransporter-2 (SGLT2) inhibitors inhibit the development of diabetic nephropathy (DN). We determined whether changes in perirenal fat (PRAT) by a SGLT2 inhibitor ipragliflozin (Ipra) contribute to the suppression of DN development. High-fat diet (HFD)-fed mice were used as a DN mode...

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Detalles Bibliográficos
Autores principales:	Okuma, Hideyuki, Mori, Kentaro, Nakamura, Suguru, Sekine, Tetsuo, Ogawa, Yoshihiro, Tsuchiya, Kyoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304702/ https://www.ncbi.nlm.nih.gov/pubmed/34298949 http://dx.doi.org/10.3390/ijms22147329

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