Altered Ca(2+) Handling and Oxidative Stress Underlie Mitochondrial Damage and Skeletal Muscle Dysfunction in Aging and Disease

Skeletal muscle contraction relies on both high-fidelity calcium (Ca(2+)) signals and robust capacity for adenosine triphosphate (ATP) generation. Ca(2+) release units (CRUs) are highly organized junctions between the terminal cisternae of the sarcoplasmic reticulum (SR) and the transverse tubule (T...

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Detalles Bibliográficos
Autores principales: Michelucci, Antonio, Liang, Chen, Protasi, Feliciano, Dirksen, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304741/
https://www.ncbi.nlm.nih.gov/pubmed/34203260
http://dx.doi.org/10.3390/metabo11070424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304741/
https://www.ncbi.nlm.nih.gov/pubmed/34203260
http://dx.doi.org/10.3390/metabo11070424

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