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SARS-CoV-2 Cellular Entry Is Independent of the ACE2 Cytoplasmic Domain Signaling

Recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV)-1 and -2 initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor angiotensin-converting enzyme 2 (ACE2) and enter into the host cells mainly via the clathrin-mediated endocytosis pathway....

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Detalles Bibliográficos
Autores principales: Karthika, Thankamani, Joseph, Jeswin, Das, V. R. Akshay, Nair, Niranjana, Charulekha, Packirisamy, Roji, Melvin Daniel, Raj, V. Stalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304749/
https://www.ncbi.nlm.nih.gov/pubmed/34359983
http://dx.doi.org/10.3390/cells10071814