Toll-Like Receptor 9-Mediated Neuronal Innate Immune Reaction Is Associated with Initiating a Pro-Regenerative State in Neurons of the Dorsal Root Ganglia Non-Associated with Sciatic Nerve Lesion

One of the changes brought about by Wallerian degeneration distal to nerve injury is disintegration of axonal mitochondria and consequent leakage of mitochondrial DNA (mtDNA)—the natural ligand for the toll-like receptor 9 (TLR9). RT-PCR and immunohistochemical or Western blot analyses were used to...

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Detalles Bibliográficos
Autores principales: Dubový, Petr, Hradilová-Svíženská, Ivana, Brázda, Václav, Joukal, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304752/
https://www.ncbi.nlm.nih.gov/pubmed/34299065
http://dx.doi.org/10.3390/ijms22147446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304752/
https://www.ncbi.nlm.nih.gov/pubmed/34299065
http://dx.doi.org/10.3390/ijms22147446

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