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A Conceptual Framework for Integrating Cellular Protein Folding, Misfolding and Aggregation

How proteins properly fold and maintain solubility at the risk of misfolding and aggregation in the cellular environments still remains largely unknown. Aggregation has been traditionally treated as a consequence of protein folding (or misfolding). Notably, however, aggregation can be generally inhi...

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Detalles Bibliográficos
Autores principales: Choi, Seong Il, Seong, Baik L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304792/
https://www.ncbi.nlm.nih.gov/pubmed/34202456
http://dx.doi.org/10.3390/life11070605