Biomarkers for Homologous Recombination Deficiency in Cancer

DNA double-strand breaks foster tumorigenesis and cell death. Two distinct mechanisms can be activated by the cell for DNA repair: the accurate mechanism of homologous recombination repair or the error-prone non-homologous end joining. Homologous Recombination Deficiency (HRD) is associated with sen...

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Detalles Bibliográficos
Autores principales: Wagener-Ryczek, Svenja, Merkelbach-Bruse, Sabine, Siemanowski, Janna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304859/
https://www.ncbi.nlm.nih.gov/pubmed/34203281
http://dx.doi.org/10.3390/jpm11070612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304859/
https://www.ncbi.nlm.nih.gov/pubmed/34203281
http://dx.doi.org/10.3390/jpm11070612

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