Mutated p53 in HGSC—From a Common Mutation to a Target for Therapy

SIMPLE SUMMARY: Ovarian high-grade serous cancer (HGSC), the most common and the deadliest subtype of epithelial ovarian cancer, is characterized by frequent mutations in the TP53 tumor suppressor gene, encoding for the p53 protein in nearly 100% of cases. This makes p53 the focus of many studies tr...

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Detalles Bibliográficos
Autores principales: Saleh, Aya, Perets, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304959/
https://www.ncbi.nlm.nih.gov/pubmed/34298679
http://dx.doi.org/10.3390/cancers13143465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304959/
https://www.ncbi.nlm.nih.gov/pubmed/34298679
http://dx.doi.org/10.3390/cancers13143465

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