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Mutated p53 in HGSC—From a Common Mutation to a Target for Therapy
SIMPLE SUMMARY: Ovarian high-grade serous cancer (HGSC), the most common and the deadliest subtype of epithelial ovarian cancer, is characterized by frequent mutations in the TP53 tumor suppressor gene, encoding for the p53 protein in nearly 100% of cases. This makes p53 the focus of many studies tr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304959/ https://www.ncbi.nlm.nih.gov/pubmed/34298679 http://dx.doi.org/10.3390/cancers13143465 |