Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies, with a five-year survival rate of only ~10%. Pancreatic tissue becomes increasingly fibrotic (known as desmoplasia) during cancer development and progression. This extensive, heterogeneous reaction...

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Detalles Bibliográficos
Autores principales: Murphy, Kendelle J., Chambers, Cecilia R., Herrmann, David, Timpson, Paul, Pereira, Brooke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305001/
https://www.ncbi.nlm.nih.gov/pubmed/34298706
http://dx.doi.org/10.3390/cancers13143481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305001/
https://www.ncbi.nlm.nih.gov/pubmed/34298706
http://dx.doi.org/10.3390/cancers13143481

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