Cytoprotective Effect of Vitamin D on Doxorubicin-Induced Cardiac Toxicity in Triple Negative Breast Cancer

Background: Doxorubicin (Dox) is a first-line treatment for triple negative breast cancer (TNBC), but its use may be limited by its cardiotoxicity mediated by the production of reactive oxygen species. We evaluated whether vitamin D may prevent Dox-induced cardiotoxicity in a mouse TNBC model. Metho...

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Detalles Bibliográficos
Autores principales: Lee, Kevin J, Wright, Griffin, Bryant, Hannah, Wiggins, Leigh Ann, Dal Zotto, Valeria L., Schuler, Michele, Malozzi, Christopher, Cohen, Michael V, Gassman, Natalie R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305038/
https://www.ncbi.nlm.nih.gov/pubmed/34299059
http://dx.doi.org/10.3390/ijms22147439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305038/
https://www.ncbi.nlm.nih.gov/pubmed/34299059
http://dx.doi.org/10.3390/ijms22147439

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