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Comprehensive Evaluation of Biological Effects of Pentathiepins on Various Human Cancer Cell Lines and Insights into Their Mode of Action

Pentathiepins are polysulfur-containing compounds that exert antiproliferative and cytotoxic activity in cancer cells, induce oxidative stress and apoptosis, and inhibit glutathione peroxidase (GPx1). This renders them promising candidates for anticancer drug development. However, the biological eff...

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Detalles Bibliográficos
Autores principales: Wolff, Lisa, Bandaru, Siva Sankar Murthy, Eger, Elias, Lam, Hoai-Nhi, Napierkowski, Martin, Baecker, Daniel, Schulzke, Carola, Bednarski, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305076/
https://www.ncbi.nlm.nih.gov/pubmed/34299253
http://dx.doi.org/10.3390/ijms22147631