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Genomic Risk Prediction for Breast Cancer in Older Women

SIMPLE SUMMARY: We designed a study specifically to assess the performance of genomic risk prediction for breast cancer (BC) in older women aged ≥70 years. We assessed the effects of a polygenic risk score (PRS) for BC and rare pathogenic variants (PVs) in BC susceptibility genes, on incident BC ris...

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Detalles Bibliográficos
Autores principales: Lacaze, Paul, Bakshi, Andrew, Riaz, Moeen, Orchard, Suzanne G., Tiller, Jane, Neumann, Johannes T., Carr, Prudence R., Joshi, Amit D., Cao, Yin, Warner, Erica T., Manning, Alisa, Nguyen-Dumont, Tú, Southey, Melissa C., Milne, Roger L., Ford, Leslie, Sebra, Robert, Schadt, Eric, Gately, Lucy, Gibbs, Peter, Thompson, Bryony A., Macrae, Finlay A., James, Paul, Winship, Ingrid, McLean, Catriona, Zalcberg, John R., Woods, Robyn L., Chan, Andrew T., Murray, Anne M., McNeil, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305131/
https://www.ncbi.nlm.nih.gov/pubmed/34298747
http://dx.doi.org/10.3390/cancers13143533