YTHDF1 Promotes Cyclin B1 Translation through m(6)A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation

KRAS and TP53 mutations are the two most common driver mutations in patients with lung adenocarcinoma (LUAD), and they appear to reduce latency and increase metastatic proclivity when a KRAS and TP53 co-mutation (KRAS/TP53-mut) occurs. However, the molecular mechanism involved is unclear. N(6)-methy...

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Detalles Bibliográficos
Autores principales: Lou, Xiaoying, Ning, Jinfeng, Liu, Wei, Li, Kexin, Qian, Benheng, Xu, Danfei, Wu, Yue, Zhang, Donghong, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305181/
https://www.ncbi.nlm.nih.gov/pubmed/34359836
http://dx.doi.org/10.3390/cells10071669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305181/
https://www.ncbi.nlm.nih.gov/pubmed/34359836
http://dx.doi.org/10.3390/cells10071669

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