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YTHDF1 Promotes Cyclin B1 Translation through m(6)A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation

KRAS and TP53 mutations are the two most common driver mutations in patients with lung adenocarcinoma (LUAD), and they appear to reduce latency and increase metastatic proclivity when a KRAS and TP53 co-mutation (KRAS/TP53-mut) occurs. However, the molecular mechanism involved is unclear. N(6)-methy...

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Detalles Bibliográficos
Autores principales:	Lou, Xiaoying, Ning, Jinfeng, Liu, Wei, Li, Kexin, Qian, Benheng, Xu, Danfei, Wu, Yue, Zhang, Donghong, Cui, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305181/ https://www.ncbi.nlm.nih.gov/pubmed/34359836 http://dx.doi.org/10.3390/cells10071669

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