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HGF/MET Axis Induces Tumor Secretion of Tenascin-C and Promotes Stromal Rewiring in Pancreatic Cancer

SIMPLE SUMMARY: It has been previously shown that activation of the MET receptor by its ligand, the hepatocyte growth factor (HGF), modulates the tumor-stroma cross-talk in models of pancreatic cancer. We now wish to cast light on the molecular mechanisms by which this ligand/receptor pair sustains...

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Detalles Bibliográficos
Autores principales: Modica, Chiara, Olivero, Martina, Zuppini, Francesca, Milan, Melissa, Basilico, Cristina, Vigna, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305254/
https://www.ncbi.nlm.nih.gov/pubmed/34298732
http://dx.doi.org/10.3390/cancers13143519