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Deficiency of IL-27 Signaling Exacerbates Experimental Autoimmune Uveitis with Elevated Uveitogenic Th1 and Th17 Responses

Human uveitis is an autoimmune disease of the central nervous system that is characterized by ocular inflammation with the involvement of uveitogenic Th1 and Th17 responses. In experimental autoimmune uveitis (EAU), the animal model for human uveitis, both responses are proven to be critical in dise...

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Detalles Bibliográficos
Autores principales: Wu, Sihan, Ma, Rui, Zhong, Yajie, Chen, Zilin, Zhou, Hongyan, Zhou, Minyi, Chong, Waipo, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305313/
https://www.ncbi.nlm.nih.gov/pubmed/34299138
http://dx.doi.org/10.3390/ijms22147517