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Imputing the Number of Responders from the Mean and Standard Deviation of CGI-Improvement in Clinical Trials Investigating Medications for Autism Spectrum Disorder

Introduction: Response to treatment, according to Clinical Global Impression-Improvement (CGI-I) scale, is an easily interpretable outcome in clinical trials of autism spectrum disorder (ASD). Yet, the CGI-I rating is sometimes reported as a continuous outcome, and converting it to dichotomous would...

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Detalles Bibliográficos
Autores principales: Siafis, Spyridon, Rodolico, Alessandro, Çıray, Oğulcan, Murphy, Declan G., Parellada, Mara, Arango, Celso, Leucht, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305379/
https://www.ncbi.nlm.nih.gov/pubmed/34356141
http://dx.doi.org/10.3390/brainsci11070908