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A Combination of GM-CSF and Released Factors from Gamma-Irradiated Tumor Cells Enhances the Differentiation of Macrophages from Bone Marrow Cells and Their Antigen-Presenting Function and Polarization to Type 1

Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes dendritic cell differentiation from precursors, and consequently, enhances the antigen presentation process and adaptive immune responses. With such functions, GM-CSF has been used as immunotherapy in combination with radiotherapy fo...

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Detalles Bibliográficos
Autores principales: Chen, Lichao, Imamichi, Shoji, Tong, Ying, Sasaki, Yuka, Onodera, Takae, Nakamura, Satoshi, Igaki, Hiroshi, Itami, Jun, Masutani, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305403/
https://www.ncbi.nlm.nih.gov/pubmed/34357151
http://dx.doi.org/10.3390/medicines8070035