Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas

As the cornerstone of high-grade glioma (HGG) treatment, radiotherapy temporarily controls tumor cells via inducing oxidative stress and subsequent DNA breaks. However, almost all HGGs recur within months. Therefore, it is important to understand the underlying mechanisms of radioresistance, so that...

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Detalles Bibliográficos
Autores principales: Cook, Kristina M., Shen, Han, McKelvey, Kelly J., Gee, Harriet E., Hau, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305417/
https://www.ncbi.nlm.nih.gov/pubmed/34298883
http://dx.doi.org/10.3390/ijms22147265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305417/
https://www.ncbi.nlm.nih.gov/pubmed/34298883
http://dx.doi.org/10.3390/ijms22147265

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