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Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas
As the cornerstone of high-grade glioma (HGG) treatment, radiotherapy temporarily controls tumor cells via inducing oxidative stress and subsequent DNA breaks. However, almost all HGGs recur within months. Therefore, it is important to understand the underlying mechanisms of radioresistance, so that...
Autores principales: | Cook, Kristina M., Shen, Han, McKelvey, Kelly J., Gee, Harriet E., Hau, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305417/ https://www.ncbi.nlm.nih.gov/pubmed/34298883 http://dx.doi.org/10.3390/ijms22147265 |
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