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A Beckwith–Wiedemann-Associated CDKN1C Mutation Allows the Identification of a Novel Nuclear Localization Signal in Human p57(Kip2)

p57(Kip2) protein is a member of the CIP/Kip family, mainly localized in the nucleus where it exerts its Cyclin/CDKs inhibitory function. In addition, the protein plays key roles in embryogenesis, differentiation, and carcinogenesis depending on its cellular localization and interactors. Mutations o...

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Detalles Bibliográficos
Autores principales: Stampone, Emanuela, Bencivenga, Debora, Barone, Clementina, Di Finizio, Marilena, Della Ragione, Fulvio, Borriello, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305445/
https://www.ncbi.nlm.nih.gov/pubmed/34299047
http://dx.doi.org/10.3390/ijms22147428