Changes to the identity of EndoC-βH1 beta cells may be mediated by stress-induced depletion of HNRNPD

BACKGROUND: Beta cell identity changes occur in the islets of donors with diabetes, but the molecular basis of this remains unclear. Protecting residual functional beta cells from cell identity changes may be beneficial for patients with diabetes. RESULTS: A somatostatin-positive cell population was...

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Detalles Bibliográficos
Autores principales: Jeffery, Nicola, Chambers, David, Invergo, Brandon M., Ames, Ryan M., Harries, Lorna W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305497/
https://www.ncbi.nlm.nih.gov/pubmed/34301309
http://dx.doi.org/10.1186/s13578-021-00658-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305497/
https://www.ncbi.nlm.nih.gov/pubmed/34301309
http://dx.doi.org/10.1186/s13578-021-00658-6

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