Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer

Background: BRCA 1/2 mutation status has become one of the most important parameters for treatment decision in patients with epithelial ovarian cancer (EOC). The aim of this study was to compare tumor DNA with blood DNA sequencing to evaluate the reliability of BRCA tumor testing results. Methods: P...

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Detalles Bibliográficos
Autores principales: Bekos, Christine, Grimm, Christoph, Kranawetter, Marlene, Polterauer, Stephan, Oberndorfer, Felicitas, Tan, Yen, Müllauer, Leonhard, Singer, Christian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305542/
https://www.ncbi.nlm.nih.gov/pubmed/34202525
http://dx.doi.org/10.3390/jpm11070593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305542/
https://www.ncbi.nlm.nih.gov/pubmed/34202525
http://dx.doi.org/10.3390/jpm11070593

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