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Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is a long-term liver disease characterized by a progressive course of cholestasis with liver inflammation and fibrosis. Intestinal barrier dysfunction has been implicated in the pathogenesis of PSC. According to the “leaky gut” hypothesis, gut inflammation alters...

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Detalles Bibliográficos
Autores principales: D’Onofrio, Fiorella, Renga, Giorgia, Puccetti, Matteo, Pariano, Marilena, Bellet, Marina Maria, Santarelli, Ilaria, Stincardini, Claudia, Mosci, Paolo, Ricci, Maurizio, Giovagnoli, Stefano, Costantini, Claudio, Romani, Luigina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305598/
https://www.ncbi.nlm.nih.gov/pubmed/34209524
http://dx.doi.org/10.3390/cells10071622