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Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a long-term liver disease characterized by a progressive course of cholestasis with liver inflammation and fibrosis. Intestinal barrier dysfunction has been implicated in the pathogenesis of PSC. According to the “leaky gut” hypothesis, gut inflammation alters...
Autores principales: | D’Onofrio, Fiorella, Renga, Giorgia, Puccetti, Matteo, Pariano, Marilena, Bellet, Marina Maria, Santarelli, Ilaria, Stincardini, Claudia, Mosci, Paolo, Ricci, Maurizio, Giovagnoli, Stefano, Costantini, Claudio, Romani, Luigina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305598/ https://www.ncbi.nlm.nih.gov/pubmed/34209524 http://dx.doi.org/10.3390/cells10071622 |
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