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Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart

Objective: Inhibitors of the angiotensin converting enzyme (ACE) are the primarily chosen drugs to treat heart failure and hypertension. Moreover, an imbalance in tissue ACE/ACE2 activity is implicated in COVID-19. In the present study, we tested the relationships between circulating and tissue (lun...

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Detalles Bibliográficos
Autores principales: Bánhegyi, Viktor, Enyedi, Attila, Fülöp, Gábor Áron, Oláh, Attila, Siket, Ivetta Mányiné, Váradi, Csongor, Bottyán, Klaudia, Lódi, Mária, Csongrádi, Alexandra, Umar, Azeem J., Fagyas, Miklós, Czuriga, Dániel, Édes, István, Pólos, Miklós, Merkely, Béla, Csanádi, Zoltán, Papp, Zoltán, Szabó, Gábor, Radovits, Tamás, Takács, István, Tóth, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305685/
https://www.ncbi.nlm.nih.gov/pubmed/34359878
http://dx.doi.org/10.3390/cells10071708