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Autophosphorylation and Self-Activation of DNA-Dependent Protein Kinase

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a member of the phosphatidylinositol 3-kinase-related kinase family, phosphorylates serine and threonine residues of substrate proteins in the presence of the Ku complex and double-stranded DNA. Although it has been established that DNA-...

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Detalles Bibliográficos
Autor principal: Kurosawa, Aya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305690/
https://www.ncbi.nlm.nih.gov/pubmed/34356107
http://dx.doi.org/10.3390/genes12071091