4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B

The multi-target-directed ligands (MTDLs) strategy is encouraged for the development of novel modulators targeting multiple pathways in the neurodegenerative cascade typical for Alzheimer’s disease (AD). Based on the structure of an in-house irreversible monoamine oxidase B (MAO-B) inhibitor, we aim...

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Detalles Bibliográficos
Autores principales: Mazej, Tjaša, Knez, Damijan, Meden, Anže, Gobec, Stanislav, Sova, Matej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305717/
https://www.ncbi.nlm.nih.gov/pubmed/34299393
http://dx.doi.org/10.3390/molecules26144118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305717/
https://www.ncbi.nlm.nih.gov/pubmed/34299393
http://dx.doi.org/10.3390/molecules26144118

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