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Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition
Protecting telomere from the DNA damage response is essential to avoid the entry into cellular senescence and organismal aging. The progressive telomere DNA shortening in dividing somatic cells, programmed during development, leads to critically short telomeres that trigger replicative senescence an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305809/ https://www.ncbi.nlm.nih.gov/pubmed/34359923 http://dx.doi.org/10.3390/cells10071753 |