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Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris

BACKGROUND: The antimicrobial peptide LL37 is produced by white blood cells (mainly neutrophils) and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing chemotaxis of immune cells and promoting wound healing. However, the central domain of LL37...

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Detalles Bibliográficos
Autores principales: Zhan, Na, Zhang, Licong, Yang, Hong, Zheng, Yalan, Wei, Xinke, Wang, Jiajun, Shan, Anshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305873/
https://www.ncbi.nlm.nih.gov/pubmed/34301247
http://dx.doi.org/10.1186/s12934-021-01635-x