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Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris
BACKGROUND: The antimicrobial peptide LL37 is produced by white blood cells (mainly neutrophils) and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing chemotaxis of immune cells and promoting wound healing. However, the central domain of LL37...
Autores principales: | Zhan, Na, Zhang, Licong, Yang, Hong, Zheng, Yalan, Wei, Xinke, Wang, Jiajun, Shan, Anshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305873/ https://www.ncbi.nlm.nih.gov/pubmed/34301247 http://dx.doi.org/10.1186/s12934-021-01635-x |
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