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The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production

Age-related macular degeneration (AMD) occurs due to an abnormality of retinal pigment epithelium (RPE) cells that leads to gradual degeneration of the macula. Currently, AMD drug pipelines are endowed with limited options, and anti-VEGF agents stand as the dominantly employed therapy. Despite the p...

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Detalles Bibliográficos
Autores principales: Hsu, Tai-Ju, Nepali, Kunal, Tsai, Chi-Hao, Imtiyaz, Zuha, Lin, Fan-Li, Hsiao, George, Lai, Mei-Jung, Cheng, Yu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305912/
https://www.ncbi.nlm.nih.gov/pubmed/34299636
http://dx.doi.org/10.3390/molecules26144359