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The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production
Age-related macular degeneration (AMD) occurs due to an abnormality of retinal pigment epithelium (RPE) cells that leads to gradual degeneration of the macula. Currently, AMD drug pipelines are endowed with limited options, and anti-VEGF agents stand as the dominantly employed therapy. Despite the p...
Autores principales: | Hsu, Tai-Ju, Nepali, Kunal, Tsai, Chi-Hao, Imtiyaz, Zuha, Lin, Fan-Li, Hsiao, George, Lai, Mei-Jung, Cheng, Yu-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305912/ https://www.ncbi.nlm.nih.gov/pubmed/34299636 http://dx.doi.org/10.3390/molecules26144359 |
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