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KRIBB11 Induces Apoptosis in A172 Glioblastoma Cells via MULE-Dependent Degradation of MCL-1

KRIBB11, an HSF1 inhibitor, was shown to sensitize various types of cancer cells to treatment with several anticancer drugs. However, the exclusive effects of KRIBB11 in preventing the growth of glioblastoma cells and the related mechanisms have not been elucidated yet. Herein, we aimed to examine t...

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Detalles Bibliográficos
Autores principales: Yoo, Kyunghyun, Yun, Hye-Hyeon, Jung, Soon-Young, Lee, Jeong-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305965/
https://www.ncbi.nlm.nih.gov/pubmed/34299435
http://dx.doi.org/10.3390/molecules26144165