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Chondroprotective Effects of a Histone Deacetylase Inhibitor, Panobinostat, on Pain Behavior and Cartilage Degradation in Anterior Cruciate Ligament Transection-Induced Experimental Osteoarthritic Rats

Osteoarthritis (OA) is the most common articular degenerative disease characterized by chronic pain, joint inflammation, and movement limitations, which are significantly influenced by aberrant epigenetic modifications of numerous OA-susceptible genes. Recent studies revealed that both the abnormal...

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Detalles Bibliográficos
Autores principales: Wen, Zhi-Hong, Huang, Jhy-Shrian, Lin, Yen-You, Yao, Zhi-Kang, Lai, Yu-Cheng, Chen, Wu-Fu, Liu, Hsin-Tzu, Lin, Sung-Chun, Tsai, Yu-Chi, Tsai, Tsung-Chang, Jean, Yen-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306086/
https://www.ncbi.nlm.nih.gov/pubmed/34298911
http://dx.doi.org/10.3390/ijms22147290