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Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells

SIMPLE SUMMARY: Breast cancer is a leading cause of cancer-related deaths worldwide, predominantly caused by metastasis. Chemokine receptor CCR7 and its ligand CCL21 are implicated in the metastasis of breast cancer to the lymph nodes. Chemokine function is dependent upon binding to their specific c...

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Detalles Bibliográficos
Autores principales: del Molino del Barrio, Irene, Meeson, Annette, Cooke, Katie, Malki, Mohammed Imad, Barron-Millar, Ben, Kirby, John A., Ali, Simi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306094/
https://www.ncbi.nlm.nih.gov/pubmed/34298676
http://dx.doi.org/10.3390/cancers13143462