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Interaction of Pestiviral E1 and E2 Sequences in Dimer Formation and Intracellular Retention

Pestiviruses contain three envelope proteins: E(rns), E1, and E2. Expression of HA-tagged E1 or mutants thereof showed that E1 forms homodimers and -trimers. C123 and, to a lesser extent, C171, affected the oligomerization of E1 with a double mutant C123S/C171S preventing oligomerization completely....

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Detalles Bibliográficos
Autores principales: Mu, Yu, Tews, Birke Andrea, Luttermann, Christine, Meyers, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306095/
https://www.ncbi.nlm.nih.gov/pubmed/34298900
http://dx.doi.org/10.3390/ijms22147285