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Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer

One-carbon (1C) metabolism plays a key role in biological functions linked to the folate cycle. These include nucleotide synthesis; the methylation of DNA, RNA, and proteins in the methionine cycle; and transsulfuration to maintain the redox condition of cancer stem cells in the tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Takeda, Yu, Chijimatsu, Ryota, Vecchione, Andrea, Arai, Takahiro, Kitagawa, Toru, Ofusa, Ken, Yabumoto, Masami, Hirotsu, Takaaki, Eguchi, Hidetoshi, Doki, Yuichiro, Ishii, Hideshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306097/
https://www.ncbi.nlm.nih.gov/pubmed/34298902
http://dx.doi.org/10.3390/ijms22147278