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Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer
One-carbon (1C) metabolism plays a key role in biological functions linked to the folate cycle. These include nucleotide synthesis; the methylation of DNA, RNA, and proteins in the methionine cycle; and transsulfuration to maintain the redox condition of cancer stem cells in the tumor microenvironme...
Autores principales: | Takeda, Yu, Chijimatsu, Ryota, Vecchione, Andrea, Arai, Takahiro, Kitagawa, Toru, Ofusa, Ken, Yabumoto, Masami, Hirotsu, Takaaki, Eguchi, Hidetoshi, Doki, Yuichiro, Ishii, Hideshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306097/ https://www.ncbi.nlm.nih.gov/pubmed/34298902 http://dx.doi.org/10.3390/ijms22147278 |
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