Megalin, Proton Pump Inhibitors and the Renin–Angiotensin System in Healthy and Pre-Eclamptic Placentas

Soluble Fms-like tyrosine kinase-1 (sFlt-1) is increased in pre-eclampsia. The proton pump inhibitor (PPI) lowers sFlt-1, while angiotensin increases it. To investigate whether PPIs lower sFlt-1 by suppressing placental renin–angiotensin system (RAS) activity, we studied gene expression and protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yuan, Tan, Lunbo, Neuman, Rugina I., Broekhuizen, Michelle, Schoenmakers, Sam, Lu, Xifeng, Danser, A. H. Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306182/
https://www.ncbi.nlm.nih.gov/pubmed/34299027
http://dx.doi.org/10.3390/ijms22147407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306182/
https://www.ncbi.nlm.nih.gov/pubmed/34299027
http://dx.doi.org/10.3390/ijms22147407

Ejemplares similares